Which medication is classified as an atypical antidepressant that can also aid in sleep and treat hyperemesis gravidarum?

Mirtazapine, commonly known by its brand name Remeron, is classified as an atypical antidepressant and is particularly noted for its sedative properties, making it beneficial for individuals dealing with insomnia or sleep disturbances, especially during pregnancy. Its mechanism of action involves the modulation of neurotransmitters, particularly norepinephrine and serotonin, which can help improve mood while also promoting sleep.

Additionally, mirtazapine has been observed to have positive effects on nausea and vomiting, making it useful in treating hyperemesis gravidarum, a condition characterized by severe nausea and vomiting during pregnancy. Its unique profile allows it to address both mood and physical symptoms associated with this challenging condition, thus providing a dual benefit to pregnant individuals who may be experiencing both depression and severe pregnancy-related nausea.

In contrast, while other options like vortioxetine and buspirone have their uses in treating mood disorders and anxiety, they do not possess the same sedative properties or specific indication for hyperemesis gravidarum. Quetiapine, while also sedative and sometimes used off-label for mood disorders, is primarily an antipsychotic and not typically first-line for depression or nausea in pregnancy contexts.