Which of the following is an SNRI?

The choice of Effexor as an SNRI is accurate because it is classified as a serotonin-norepinephrine reuptake inhibitor. This class of medications is designed to increase the levels of both serotonin and norepinephrine in the brain, which can help in the treatment of various mood disorders, including generalized anxiety disorder and depression.

SNRIs like Effexor target both neurotransmitters, which is believed to enhance their therapeutic effects compared to those that only affect serotonin, such as selective serotonin reuptake inhibitors (SSRIs) like Sertraline. This dual action can make SNRIs particularly effective for patients who experience pain as a symptom of their depression or anxiety.

In contrast, the other options listed—Buspar (an anxiolytic), Vistaril (an antihistamine with sedative properties), and Sertraline (an SSRI)—do not fall under the SNRI classification. Each of these medications serves different purposes and operates through different mechanisms in the brain.