Which option is NOT an atypical antidepressant?

Norpramin, known generically as desipramine, is classified as a tricyclic antidepressant (TCA), which is a well-established category of antidepressants that has been used for decades. TCAs work primarily by inhibiting the reuptake of norepinephrine and serotonin, thereby increasing the levels of these neurotransmitters in the brain and helping to alleviate depressive symptoms.

In contrast, the other medications listed—Remeron (mirtazapine), Trintellix (vortioxetine), and Wellbutrin (bupropion)—are all categorized as atypical antidepressants. Atypical antidepressants do not fit neatly into the traditional categories of SSRIs, SNRIs, or TCAs, and they often have unique mechanisms of action. For example, Remeron is known for its sedative properties and works on serotonin and norepinephrine receptors in a different way than traditional antidepressants. Trintellix has a multimodal mechanism that enhances serotonin activity while also targeting other receptors. Wellbutrin primarily acts as a norepinephrine-dopamine reuptake inhibitor (NDRI).

Understanding these classifications helps in recognizing how different antidepressants interact with brain chemistry, and identifying Norpramin